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The essential role of ThDP in mitochondrial energy production (Figure 1) is universal for all tissues and therefore can hardly explain specific and primary vulnerability of the gastrointestinal system

Heart Lung Circ 19:584591 Chang C, Worley BL, Phaton R, Hempel N (2020) Extracellular glutathione peroxidase GPx3 and its role in cancer

however, a correct daily dietary intake is essential because it influences the size of a small but significant endogenous zinc pool, the so-called exchangeable zinc pool (EZP), which is probably the most important zinc reservoir (82, 83)

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