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This magnitude of effect rivals or exceeds what phentermine achieves and does so through a more sustainable, physiologically balanced mechanism

Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or References Brennan K, Lea R, Fitzmaurice P, Truman P

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Results at Week 30 in a Trial of OZEMPIC as Monotherapy in Adult Patients with Type 2 Diabetes Mellitus Inadequately Controlled with Diet and Exercise The mean baseline body weight was 89.1 kg, 89.8 kg, 96.9 kg in the placebo, OZEMPIC 0.5 mg, and OZEMPIC 1 mg arms, respectively

However, approval is conditional: adolescents must have severe obesity (BMI 35 or 95th percentile for age) and documented cardiovascular or metabolic complications such as type 2 diabetes, hypertension, or sleep apnea