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Instead, numerous small molecule inhibitors exert their anti-cancer effects through off-target interactions, with their anti-tumor activity either independent of, or partially reliant on, their intended targets [6,7,8]

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Studies have shown that adipose tissue plays an important role as a pro-inflammatory factor in the pathogenesis of PCOS, and the release of tumor necrosis factor alfa (TNF-) and interleukin-6 (IL-6) from macrophages is associated with the induction of insulin resistance (67)

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Ann Oncol 20(Suppl 6):vi51vi58 Cox NH, Aitchison TC, Sirel JM, Mackie RM (1996) Comparison between lentigo maligna melanoma and other histogenetic types of malignant melanoma of the head and neck

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The link between type 2 diabetes mellitus and the polymorphisms of glutathione-metabolizing genes suggests a new hypothesis explaining disease initiation and progression

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Vitamin B12 injections come in various preparations to meet different patient needs

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