230,231 GLP-1 RAs have been previously described in this review as improving tissue homeostasis and repair through reducing age-related inflammation (i.e., TNF- and IL-6)
For each included study, we extracted HRs with corresponding 95% CIs for outcomes of interest: AUD diagnosis and alcohol-related hospitalization
Among the ten in vivo studies, although various dosages were tested, neither a clear dose-response relationship nor long-term toxicity assessments (e.g., liver and kidney function indicators) were reported (Wang et al., 2023c
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