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Agitation: This one surprises many researchers

Regarding immune regulation, histamine possesses significant chemotactic properties, inducing the migration of immune cells via H4R, while H2R mainly mediates immunosuppressive effects 152

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Although modulating DMV Ach neurons does not directly promote mucus secretion by small intestinal goblet cells, promoting secretion via Brunners glands can lead to conditions conducive for the proliferation of lactobacilli 66