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Marihuana is listed in Schedule I of the CSA due to its high potential for abuse, which is attributable in large part to the psychoactive effects of THC, and the absence of a currently accepted medical use of the plant in the United States

Once reconstituted, always refrigerate and use within the recommended timeframe

Night-time application and alternating frequency (2-3 times weekly initially) may help minimize sensory irritation and erythema in darker skin phenotypes

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Mechanisms and therapeutic implications