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doi: 10.1016/j.cbi.2017.11.007 52 SzabelakABownikAKnagaSKasperekK

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Key symptoms of underactive thyroid Weight is easy to gain and hard to lose Brain fog and poor concentration Cold extremities and temperature sensitivity Constipation Fatigue and low energy levels High cholesterol Achy muscles Heavy periods Goitre (enlarged thyroid gland) Which nutrients support healthy thyroid function

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In endometrial stromal cells (ESC), TNF-induced activation of the estrogen receptor ER leads to heightened ERK activation (53)