The pivotal role of the Nrf2-Keap1 signaling pathway in maintaining redox, metabolic, and protein homeostasis, as well as regulating inflammation responses, has been discussed ( However, the therapeutic potential of Nrf2 activation is tempered by paradoxical risks
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In conclusion, the co-supplementation of 4 mM GSH with 2 g/ml SeNPs significantly promoted motility, viability, mitochondrial activity, plasma membrane integrity, acrosome integrity, antioxidant ability, and embryonic development potentials of cryopreserved bull spermatozoa
