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The most commonly reported adverse effects were mild to moderate headache and gastrointestinal symptoms including diarrhea, flatulence, nausea, and increased appetite

Your serum levels of B12 are notoriously inaccurate and are not necessarily a good measure of the general B12 status of your body

Avoid simultaneous use with strong acids or chelators (e.g., vitamin C or retinol serums) because they can inactivate copper peptides

But you need folate - and a wide range of vitamins and minerals - to make the B12 work properly, so if you are short of something the extra B12 might not be as effective

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