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8.7 Hepatic Impairment There is limited experience in patients with mild, moderate or severe hepatic impairment

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Many of these people may also be on an ACE inhibitor, further confusing management

We searched for approved generic competitors in the Orange Book to determine if the expected duration of protection for brand-name products had been cut short by early generic competition, and we used the FDAs Paragraph IV Certifications List (updated through the end of 2022) to identify patent challenges on brand-name products in the cohort