Abstract Aims/hypothesis Regulators worldwide are reviewing safety data on glucagon-like peptide-1 receptor agonists (GLP-1RA), following reports by the Icelandic Medicines Agency in July 2023 of suicidal ideation and self-injury (SIS) in individuals taking liraglutide and semaglutide
Do not double up the next week
Summary: The optimal timing for GLP-1 injections depends on the specific formulation, with once-weekly products like semaglutide and dulaglutide administered at any time of day, whilst consistency and adherence are the most important factors
These include changes in the size and pigmentation of moles, rapid appearance of new moles, facial flushing, abdominal cramps, nausea, vomiting, chest pain and brain swelling
Figure 3 Ultimately, while these animal models provide a mechanistic rationale for delayed exhaustion under extreme, unnatural physical stress (e.g., weighted swimming to the point of drowning), it remains highly speculative to extrapolate these rodent findings to the complex, voluntary physical performance of healthy elite human athletes
