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Unimolecular peptides with dual GIP/GLP-1 receptor agonism have been developed to improve metabolic efficacy and therapeutic index beyond what incretin mono-agonists can achieve (44, 63)

van Bommel EJM, Muskiet MHA, van Baar MJB et al (2020) The renal hemodynamic effects of the SGLT2 inhibitor dapagliflozin are caused by post-glomerular vasodilatation rather than pre-glomerular vasoconstriction in metformin-treated patients with type 2 diabetes in the randomized, double-blind RED trial

Understand reasonable pricing Affordability drives many patients toward compounded options, but extreme bargains should trigger suspicion

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As a result of the popularity of Ozempic for weight loss, Novo Nordisk has introduced a higher dose version under the brand name Wegovy, which is specifically approved as a diet drug