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Enzyme sources Pooled subcellular fractions of male Sprague-Dawley rat liver S9 fractions (10 donors), male Sprague-Dawley Aroclor 1254 induced rat liver S9 fractions (20 donors), human liver S9 fractions (mixed gender 10 donors), male Gottingen minipig liver microsomes (3 donors) and male Gottingen minipig liver S9 fractions (3 donors) were purchased from BioreclamationIVT (West Sussex, UK)

Cr concentrations were determined from PRESS spectra using standard model-fitting procedures (LCModel software version 6.2-0T (ref

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Produced in the liver, glutathione is used by every cell and tissue in the body though its intracellular levels decline naturally we get older: natural production falls by approximately 10% each decade