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In the SUSTAIN 6 trial of subcutaneous once weekly semaglutide, more retinopathy events occurred in the semaglutide group

In randomized clinical trials in adult patients, cholelithiasis was reported by 1.6% of WEGOVY-treated patients and 0.7% of placebo-treated patients

FEBS Letters 584 (2010) 29212925.

These symptoms may indicate complications requiring immediate medical evaluation and potential treatment modification or discontinuation

Oral B12 supplements rely on the digestive system for absorption, which can be significantly impaired by gut conditions, age-related changes, or the absence of intrinsic factor (a protein required for B12 absorption)