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NYHA, New York Heart Association

Two studies reported a significant reduction in lower limb amputations (LLA) and diabetic foot ulcers, while one study found no significant difference in LLA compared to other diabetic therapies

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A 40-day water-only fast by a Pentecostal woman: clinical and religious observations

The study: Ran for only three weeks Included only male mice Lost two animals from the tirzepatide group before completion Has not yet been replicated in human clinical trials involving individuals with MC4R mutations As such, the findings represent proof of biological concept rather than immediate clinical guidance