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In our study, by day 6 after irradiation, we observed a significant difference in circulating citrulline levels between the 3-Gy+MAD mice (those that did not develop GI-ARS), and the 3-Gy+MSD mice (those that developed GI-ARS with lethality at 35% by day 12 )

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Participants in the 12 mg group showed approximately 86% relative reduction in liver fat content as measured by MRI-PDFF