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Theoretically, since body weight is a key determinant of MASLD, even a 1kg difference could matter in the long term, but whether this statistically significant difference translates into clinical benefits remains uncertain

However, it is always wise to monitor your bodys response and seek professional advice if you have any medical conditions or are taking medications

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European journal of endocrinology

We also observed the ability of GLP-1(2836) to increase cAMP production through bicarbonate-responsive (i.e., probenicid-inhibited) sAC in human caECs