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Description

Elevated insulin blocks fat mobilization, rendering the peptide less effective

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The problem is in the gut, so delivering the compound directly to the gut lining is the most logical and effective approach

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These findings led to the investigation of the mechanism by which DSIP may alter mitochondrial activity in a hypoxic environment, suggesting that the peptide could also have an effect on the course of depression

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The authors reported that AOD-9604 stimulated lipolysis in isolated adipocytes and that chronic daily treatment in obese Zucker rats produced reductions in body weight gain of more than 50% relative to untreated controls over the treatment period, without effects on insulin sensitivity or IGF-1 levels [3]

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