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( 10.1016/S0140-6736(2101324-6) [DOI] [PubMed] [Google Scholar] Rosenstock J, Frias J, Jastreboff AM, Du Y, Lou J, Gurbuz S, Thomas MK, Hartman ML, Haupt A, Milicevic Z, et al

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However, several significant limitations have hampered the development of PYY 3-36 as an anti-obesity drug, including its short half-life (~ 12 min) 42 and its inability to sustain weight reduction beyond a 12-week period 43

Overall, KD shows promise as a complementary therapeutic strategy capable of targeting multiple aspects of PD pathology