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10.23937/2474-3658/1510187 J Infect Dis Epidemiol

Key determinants of AMS onset include altitude, individual sensitivity, rate of ascent, duration of stay, physical exertion levels, and adaptation to hypoxic conditions (Schneider et al., 2002

These modifications are not observed in CX3CR1 / mice, suggesting different protective roles for CD200/CD200R and CX3CL1/CX3CR1 in microglia control

Pyroptosis activation is highly dependent on direct stimulation of immune cells by pathogen-associated molecular patterns, and its core pathological effect is the massive release of potent pro-inflammatory cytokines such as IL-1 and IL-18