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Major challenges associated with long-acting formulations include high material costs, limited biomaterial availability, and system complexity

Any unusual symptoms (headache, palpitations, dizziness)

A common approach to managing the reaction includes temporarily holding the infusion, initiating the normal anaphylactic countermeasures, then restarting the infusion at half of the previous rate after symptom control

That means these people will experience a pop in energy followed by an energy crash. The vitamin B12 deficiency issue is not addressed and the person is at risk for long term damage to their body

2019;8(19):e012569