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Inflammation begins with M1 macrophages, whereas M2 macrophages facilitate fibrosis and healing

Conclusion: Rutin exerts stronger protection against nitrosative stress and hepatocellular damage but has weaker antioxidant and anti-inflammatory activities and antifibrotic potential than quercetin, which may be attributed to the presence of a rutinoside moiety in position 3 of the C ring

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This property is a focal point in studies that ways to improve immune resilience and health outcomes

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