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It needs to be tolerant

Advanced liver disease can alter the levels of B12 binding proteins in the blood, making total serum B12 measurements unreliablelevels may appear normal or even elevated despite functional deficiency

DSIP is supplied as a lyophilized that is, freeze-dried powder in sealed vials

J Appl Toxicology: JAT

Catalase, a tetrameric ferriheme oxidoreductase, facilitates the breakdown of hydrogen peroxide into water and oxygen (259) Glutathione peroxidase, a selenium-dependent oxidoreductase, utilises hydrogen peroxide or organic hydroperoxides as substrates, with reduced glutathione (GSH) acting as the electron donor (260) The reactions include: H 2 O 2 + 2GSH 2H 2 O + GSSG and ROOH + 2GSH ROH + H 2 O + GSSG (261, 262)