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Vas ms afectadas: Regulacin al alza: reparacin de DNA, respuesta antioxidante (NRF2), sntesis de matriz extracelular (colgeno I, III, IV, decorina, glicosaminoglicanos), antiapoptosis

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FDA www.accessdata.fda.gov/drugsatfda_docs/nda/2005/21-332_Symlin%20Injection_prntlbl.pdf (2005)