The Conversation Gets More Complicated One reason this topic has become so challenging is that stopping GLP-1 medications may also carry consequences
These results indicate that FA metabolism, especially uptake of FA, in the adipocyte-rich TME plays a crucial role in the formation of CD8 + Tsen, and its formation can be decreased and resulted anti-tumor immunity can be enhanced by intervening in FA uptake
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This may lead to increased caloric intake, potentially undermining weight management goals and glycaemic control
Once weight stabilizes, usually 12-18 months into therapy, some supplement doses can be reduced based on blood work