About the authorView full bio Michael Stewart, MRPharmS Medicine Leaflet Review Manager Contractor, Pharmacist BPharm (Hons), MRPharmS Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years experience advising on medicines and medical conditions
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Interestingly, the strong dependence of mitochondrial -oxidation on autophagic and fatty acid (FA) catabolic processes makes some tumors more resistant to nutrient deprivation and environmental stressors 13
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77,83,84 In addition, the expression of ALDH1L2 is upregulated by some certain drugs, such as thapsigargin and tunicamycin, endoplasmic reticulum stress inducers in immortalized human B cells, 85 mitotane, an adjuvant monotherapy used for treating adrenocortical carcinoma, 86 and the indomethacin, an anti-inflammatory agent in breast cancer cells