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Ketamine reduces inflammation-induced QA elevations, with QA reductions correlating with symptom improvement, and KYNA/QA ratios have been shown to predict ketamine responsiveness, linking KP modulation to clinical outcomes [205, 206]

In S2 overall, Ex still caused strong, significant decrements in food consumption (against Vehicle: F 1.7,6.8 = 22.86, p = 0.001

doi: 10.1371/journal.pbio.1000441 51 MrkusR.LaurinyeczB.KuruczE.HontiV.BajuszI.SiposB.et al

Individual health factors determine the best transition approach