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Purushothuman S, Nandasena C, Peoples CL, El Massri N, Johnstone DM, Mitrofanis J, Stone J

FSH acts in Sertoli cells by stimulating signaling, gene expression, and the secretion of peptides and other signaling molecules (12) In Sertoli cells, i.e., the cAMP response element binding protein (CREB) transcription factor, an important transducer of FSH signals

Three caveats matter: Bioavailability stays below injectable

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Intranasal delivery allows for rapid absorption, making this formulation ideal for patients seeking fast-acting, non-invasive support in functional or integrative sexual wellness protocols