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Many insurers are pulling coverage for GLP-1 drugs due to their high price, forcing patients to stop treatment even when it works

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It is a calculated estimate of insulin sensitivity derived from two simple lab values: Fasting insulin (U/mL) Fasting glucose (mg/dL) / 405 It doesn't require complex imaging, clamp studies, or invasive procedures

Following oral administration, the drug must be absorbed across the walls of the GI tract and then must escape metabolism as it passes through the liver, in order to reach the systemic circulation

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