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634 AAK1 inhibitor LX-9211: Junctional protein 2-associated kinase 1 (AAK1) is widely expressed in the brain and spinal cord and is a viable target for the treatment of neuropathic pain, and BMS-986176/LX-9211 is a novel class of bis(iso)aryl ethers that are highly selective, CNS-permeable, and potent AAK1 inhibitors

It is critical for both innate and adaptive immunity, specifically helping T-cells function properly

The phospholipid bilayer of liposomes resists the catabolic effects of gastric acid and digestive enzymes, allowing glutathione to reach absorption sites such as the small intestine intact

Biophys J 121:21682179

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