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Flow cytometry of ALL during induction therapy and multivariate analysis of prognostic factors

Progressive serum HBsAg reduction was closely paralleled with progressive serum HBeAg decline, implying that progressive serum HBsAg reduction reflects progressive HBV clearance in the livers, which was confirmed by a 3-4 log lower intrahepatic HBsAg, rc, and cccDNA levels from mice who achieved undetectable serum HBsAg compared to untreated controls

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