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Why Ozempic is Not Prescribed for Weight Loss at Klinic Ozempic and Wegovy share semaglutide, but serve different roles

Target Concerns: Dullness, dark spots, uneven tone, melasma, dehydration, loss of radiance, UV damage, premature aging, pollution stress

Participants experienced as much as 24 percent body weight loss at 48 weeks at higher doses

For people on medications like semaglutide (Ozempic, Wegovy), tirzepatide (Mounjaro, Zepbound), and orforglipron (Foundayo), experts say its vital to have strategies in place to prevent dehydration, which can pose serious health risks

This observation has raised concerns regarding suboptimal drug exposure, altered pharmacokinetics, and heightened inflammatory burden in obese patients, highlighting the potential need for dose optimization or alternative treatment strategies in this population ( The impact of BMI on treatment response is well illustrated by the AQUILA study, which examined real-world outcomes in PsA patients treated with (65).In this cohort, obese individuals exhibited higher circulating levels of IL-17, supporting the concept that IL-17driven inflammation may be particularly prominent in this subgroup and may contribute to increased disease activity and reduced therapeutic responsiveness (66)