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Only studies involving adults ( 18 years) were included to avoid the heterogeneity introduced by juvenile or atypical Parkinsonian syndromes, which may differ in aetiology, progression, and treatment response

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Krbling, M, Engel H, van Besien K, Huh YO, Przepiorka D Giralt S, Kleine HD, Seong D, Deisseroth A, Andreeff M , Champlin R