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Protocol design implications 13

Children with MIS-C need close observation by pediatric specialists in rheumatology, cardiology, critical care, and sometimes hematologists and infectious disease doctors

doi:10.1016/j.jri.2024.104221

This bidirectional signaling between the brain and the intestine is essentially in tandem in the neural, endocrine, and immune pathways ( via the vagal and spinal nerves, plays a role in regulating the sensory, motor, and secretory functions of the digestive system ( 4.1.6 Gutliverbone axis As emphasized above, the activation of vitamin D from intestinal sources depends on the support of the liver

That compared with about 25% of participants who were administered a placebo