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CNM-Au8: Biomarker-Driven Accelerated-Approval Bid in ALS (Clene Nanomedicine) CNM-Au8 is an investigational therapy for ALS supported by FDA-recommended analyses showing significant reductions in two biomarkers of nerve injury and inflammation: neurofilament light (NfL) and glial fibrillary acidic protein (GFAP)

Yes, a split-dosing protocol (e.g., one dose in the morning, one in the evening) is an effective strategy for research on chronic conditions

Frontiers in Pharmacology, 2017, 8: 904

Bulletin of Experimental Biology and Medicine, 2003

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