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Speaking of HMB, dietitian Destini Moody, RD, CSSD, LD, likes the addition of calcium and HMB, as she notes, Some research 11 shows that calcium and creatine can work together to support bone health and produce more efficient muscle contractions. HMB has also been shown to support hypertrophy and enhance muscle growth when taken with creatine 3

doi:10.1038/ijo.2013.152

These medications are intended as an adjunct to a reduced-calorie diet and increased physical activity, not as standalone treatments