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Using a collagen gel contraction assay, we observed that primary fibroblasts from the lungs of aged GHK-treated mice exhibited enhanced contraction compared to fibroblasts from placebo-treated mice (Figure 4), further supporting the hypothesis that GHK promotes the resolution of collagen scars

People with uncontrolled high blood pressure or known cardiovascular disease should not take PT-141 because the medication increases blood pressure and reduces heart rate after each dose

This avoids stomach irritation and ensures steady absorption

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In certain circumstancessuch as pregnancy, concurrent illness, or rapid metabolic turnoverB12 requirements may increase, and dosing adjustments may be necessary under medical supervision