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Its exact mechanism of action in promoting weight loss is not fully understood, but it is thought to involve appetite suppression and modulation of certain neurotransmitter systems

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In sum, the combined effects of RE and RE-induced testosterone release induced upregulation of AR anabolism is driven via genomic and non-genomic signaling pathways which likely augment protein turnover in muscle resulting in increases in net protein accretion and hypertrophy (Wolfe et al., 2000