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Huwiler VV, Maissen-Abgottspon S, Stanga Z, Mhlebach S, Trepp R, Bally L et al (2024) Selenium Supplementation in Patients with Hashimoto Thyroiditis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

This allows clear identification of which compound causes any effects

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Addition of free ligands inhibited the cellular internalization of targeted nanocarriers suggesting the crucial role of ligands in the uptake process

The process is called Autophagy and in fact they're already doing a first in-human safety trial of an Alzheimer's drug