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The filter as claimed in claim 1, wherein the smoke containing very low level of p-BSQ is incapable of producing significant oxidative damage to the lung microsomal proteins of guinea pigs when said guinea pigs are exposed to smoke emitted from said charcoal-filtered tobacco smoke devices in contrast to marked damage of the lung tissue when the guinea pigs are exposed to smoke from tobacco smoke devices without having the charcoal filter

Sales were slow at first: customers didnt understand what the product was, and many Americans still associated oral nicotine products with oral cancer

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