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For other uses, it is recommended to test a small amount prior to full scale use

Best for harm reduction without quitting nicotine

Since many communities, professions, and subject disciplines have developed different ways to classify things and organize knowledge, the high-level effort of promoting a unified classification system such as ICD is critical, as it provides a common language for reporting and monitoring diseases and has been used worldwide for morbidity and mortality statistics

Some benefits people report: reduced dependence, ability to enjoy flavor without nicotine, less harsh throat hit, possibly lower cost if nicotine-free fluids are cheaper, and fewer regulatory issues depending on the region

Cohen RT, Strunk RC, Field JJ, Rosen CL, Kirkham FJ, Redline S, et al