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36 , 37 Nicotine also enhances behavioral responses to conditioned stimuli, which may contribute to compulsive smoking
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Across 17 clinical trials, we found minimal evidence that this happens. In the systematic review, Denlinger-Apte and colleagues examined clinical trials published between 2010 and 2024 and also performed an analysis using data from more than 2,400 smokers enrolled in seven U.S
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