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Smoking (including active and passive smoking) can not only cause frequent attacks of asthma, lead to rapid decline of lung function in asthmatic patients, but also reduce the therapeutic effect of glucocorticoid in asthmatic patients, making the condition of asthmatic patients difficult to control [102]

Meta- and pooled analyses of the effects of glutathione- S -transferase M1 polymorphisms and smoking on lung cancer risk

Medline:27158893 doi:10.1002/14651858.CD006103.pub7 66

Despite that, the disclaimer only addressed the lack of additives

At the same time, water stress triggers the expression of genes regulated by both abscisic acid-dependent and independent signaling pathways