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OK, so no smoking gun

Its just been a big part of my life, reluctantly, because Ive been addicted to cigarettes for a long time

Smokers usually have chronic bad breath and discolored teeth because these chemicals cause a significant reduction of saliva flow

non-smokers 24 , and the striatum is widely considered to be a key set of brain structures that support addiction 25,26,27 , with interactions between nicotine and the mesolimbic dopamine system also well-established (for a review see 28 )