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3.2.3.1 Oxidative stress regulation and mitochondrial protection HS mediates cardioprotection through dual antioxidant mechanisms: direct ROS scavenging and enhancement of the endogenous antioxidant system, thereby establishing a synergistic defense network for oxidative stress regulation and mitochondrial protection

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490 The ability of iron chelators or ferroptosis inhibitors to reverse cardiac damage during both acute and chronic I/R injury highlights ferroptosis as a promising new treatment strategy for myocardial I/R injury