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In the case of amyloid b-protein (A) aggregates and tau hyper-phosphorylation (p-tau) induced pathogenesis, neuronal damage occurred through proinflammatory cytokines (IL1, IL6, and TNF-) or increased activity of CDK5 and P38 [199]

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Lori Shah, a transplant pulmonologist at New York-Presbyterian/Columbia University Irving Medical Center