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Acrylonitrile is typically used in the manufacturer of plastics and fibers

Long-term use can cause phentermine addiction and physical dependence

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The overall aims of this study were to (i) investigate smoke exposure impairs the bone remodeling through induction of bone resorption and inhibition of bone formation in vivo, (ii) determine the mechanisms of how smoke exposure affects bone remodeling in vitro at both cellular and molecular levels