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Behavioral changes have also been observed even in the absence of nicotine, as nicotine-free electronic cigarette vapor exposure was shown to result in anxiogenic phenotypes in both male and female mice (81)

The Juul refills, called pods, can contain the same amount of nicotine as 20 cigarettes

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5 June 2026 12 Natural Ways to Keep Your Heart Healthy Cardiovascular diseases are increasingly affecting people during their most active working years