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The concern would be that, for nonsmokers and teens, e-cigs become a gateway to nicotine addiction. In addition, the long-term effects of substances found in vape liquids, like propylene glycol, are still unknown, so until we have more definitive data, caution is the watchword

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doi: 10.1159/000316356 118 GentileVNicotraMMinucciSAmbrosiSSaccucciPGloria-BottiniFet al