During traditional dieting, falling leptin triggers hunger and metabolic slowdown
Recently, copper-related mechanisms have been suggested as therapeutic targets for important indications such as cancer [33], microbial defence [34,35,36,37], chronic lung inflammation [38], influenza A [39], neurodegenerative diseases including Alzheimers disease (AD), Parkinsons disease (PD) and prion disease along with disorders linked to copper homeostasis such as Menkes disease (MD) or Wilsons disease (WD) [40,41,42,43]
PortuneKJBeaumontMDavilaAMTomDBlachierFSanzY
Journal of pharmacological sciences , 108 (1), 7-17
Gastrointestinal discomfort, including mild nausea or stomach upset, has been noted in anecdotal accounts, though no severe gastrointestinal effects have been documented in controlled studies